Dr Colm Cunningham is an Associate Professor in the School of Biochemistry and Immunology in Trinity College Dublin. His main research interest is to develop and study animal models to understand the impact of inflammation, and in particular, of systemic inflammation on brain function and neurodegeneration.
Dr Cunningham trained for a Ph.D. in the neurochemistry laboratory of Keith Tipton in TCD before spending 8 years working with Prof. Hugh Perry’s CNS inflammation group in the University of Southampton, where he first described microglial priming during chronic neurodegeneration. In 2006 and 2010 the Wellcome Trust awarded him Career Development and Senior Fellowships to establish and develop the first animal models of delirium during dementia in Trinity College Dublin.
The interaction between prior neurodegenerative pathology and superimposed secondary insults in delirium and long-term cognitive decline is now the major focus of his work and his lab is currently supported by the US National Institute of Aging (NIH), the Simons Foundation and Alzheimer’s Research UK.